Best NAD+ Supplements Ranked (2026)
Comprehensive ranking of NAD+ supplements: Tru Niagen, Elysium Basis, Alive by Science, ProHealth, and Renue. Ranked by dose, evidence, and price.
How We Rank
Every product in this comparison is evaluated on a consistent framework: clinical evidence (human trials weighted over animal studies), ingredient quality and bioavailable forms, dosing adequacy relative to clinical thresholds, third-party testing certifications, and price-per-serving in context.
Key Factors in This Category
For this comparison, we focused specifically on the most evidence-critical factors: mechanism of action, peer-reviewed human trial data, ingredient sourcing and forms, dose matching to clinical studies, and independent certification (NSF, Informed Sport, USP).
Our Rankings
Based on our framework analysis, see our full reviews section for individual brand deep-dives that inform this comparison. The rankings here represent our editorial team's consensus assessment weighted by evidence quality.
Best For: Persona Breakdown
Evidence-first buyer: Choose the brand with the most published human trial data for your specific health goal. For NAD+, that is NR (Tru Niagen).
Comprehensiveness buyer: Consider bundled formulas (AG1, Lifeforce) for convenience, accepting some trade-off on individual dose optimization.
Cost-optimizer: Build your own stack from best-in-class individual supplements - typically delivers better per-ingredient value than pre-made stacks.