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NAD+ Supplement

Elysium Basis Review (2026)

★★★★☆

Scientist-founded NAD+ formula combining NR and pterostilbene. Credible science, but proprietary dosing limits transparency.

Buy at Elysium → Amazon
4.3
TL;DR

Pros

  • NR + pterostilbene synergy (sirtuin activation)
  • Co-founded by Nobel laureates
  • One published clinical trial

Cons

  • 250mg NR - slightly below optimal dose
  • Pterostilbene dose not disclosed
Best for: Buyers who want both NR and pterostilbene in a single capsule and trust the Elysium brand heritage.
Skip if: You want maximum NR dose - Tru Niagen gives you 300mg vs Elysium's 250mg.

What Is Elysium Basis?

Elysium Health was co-founded by MIT biologist Leonard Guarente and has an advisory board including Nobel laureates. Basis is their flagship product: a combination of nicotinamide riboside (NR) and pterostilbene, designed to raise NAD+ levels while activating sirtuins through two complementary mechanisms.

Pterostilbene is a methylated analog of resveratrol with superior bioavailability. Resveratrol activates SIRT1; pterostilbene does the same with better absorption and duration. The combination with an NAD+ precursor creates a sirtuin activation strategy that targets both the substrate (NAD+) and the enzyme (SIRT1).

Ingredients & Dosing

IngredientDoseClinical doseAssessment
Nicotinamide Riboside (NR)250mg250-300mg✓ Adequate
PterostilbeneProprietary50-100mg⚠ Undisclosed

Clinical Evidence

Elysium conducted a double-blind, randomized trial (Dellinger et al., 2017) showing Basis elevated whole blood NAD+ by 40% at 250mg/day, and 90% at 500mg/day over 8 weeks - comparable to Tru Niagen's results. However, this is a single company-funded trial, contrasted with multiple independent studies validating NR generally.

Verdict

Elysium Basis is a legitimate, well-formulated product. The NR + pterostilbene combination is scientifically sound. Our 4.3/5 reflects the strong brand credibility and functional formula, docked slightly for proprietary pterostilbene dosing and slightly lower NR content vs Tru Niagen. At similar pricing, the choice comes down to whether you value the pterostilbene synergy (Basis) or maximum NR dose (Tru Niagen).

Frequently Asked Questions

Elysium Basis vs Tru Niagen - which is better?
Tru Niagen has more human trial data (5+ studies) and delivers 300mg NR. Elysium Basis delivers 250mg NR plus pterostilbene, which may provide additive sirtuin activation. If NAD+ elevation is the only goal, Tru Niagen edges ahead. If you want the combined NR + sirtuin activator approach, Basis is a scientifically reasonable choice.
What does pterostilbene do?
Pterostilbene is a stilbenoid (related to resveratrol) that activates SIRT1, an NAD+-dependent deacetylase involved in gene expression regulation, inflammation control, and metabolic function. It has higher bioavailability than resveratrol (80% vs ~1% for resveratrol) and a longer half-life.
Is Elysium Basis subscription-only?
No - you can buy single bottles at a higher per-unit price. The subscription ($45/month) offers better value. Elysium periodically discounts annual plans.